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1.

Small Molecules Co-targeting CKIα and the Transcriptional Kinases CDK7/9 Control AML in Preclinical Models.

Minzel, Waleed; Venkatachalam, Avanthika; Fink, Avner; Hung, Eric; Brachya, Guy; Burstain, Ido; Shaham, Maya; Rivlin, Amitai; Omer, Itay; Zinger, Adar; Elias, Shlomo; Winter, Eitan; Erdman, Paul E; Sullivan, Robert W; Fung, Leah; Mercurio, Frank; Li, Dansu; Vacca, Joseph; Kaushansky, Nathali; Shlush, Liran; Oren, Moshe; Levine, Ross; Pikarsky, Eli; Snir-Alkalay, Irit; Ben-Neriah, Yinon.

Cell ; 175(1): 171-185.e25, 2018 09 20.

Article in English | MEDLINE | ID: mdl-30146162

2.

Inflammatory networks underlying colorectal cancer.

Lasry, Audrey; Zinger, Adar; Ben-Neriah, Yinon.

Nat Immunol ; 17(3): 230-40, 2016 Mar.

Article in English | MEDLINE | ID: mdl-26882261

3.

Ectopic lymphoid structures function as microniches for tumor progenitor cells in hepatocellular carcinoma.

Finkin, Shlomi; Yuan, Detian; Stein, Ilan; Taniguchi, Koji; Weber, Achim; Unger, Kristian; Browning, Jeffrey L; Goossens, Nicolas; Nakagawa, Shigeki; Gunasekaran, Ganesh; Schwartz, Myron E; Kobayashi, Masahiro; Kumada, Hiromitsu; Berger, Michael; Pappo, Orit; Rajewsky, Klaus; Hoshida, Yujin; Karin, Michael; Heikenwalder, Mathias; Ben-Neriah, Yinon; Pikarsky, Eli.

Nat Immunol ; 16(12): 1235-44, 2015 Dec.

Article in English | MEDLINE | ID: mdl-26502405

4.

The gut microbiome switches mutant p53 from tumour-suppressive to oncogenic.

Kadosh, Eliran; Snir-Alkalay, Irit; Venkatachalam, Avanthika; May, Shahaf; Lasry, Audrey; Elyada, Ela; Zinger, Adar; Shaham, Maya; Vaalani, Gitit; Mernberger, Marco; Stiewe, Thorsten; Pikarsky, Eli; Oren, Moshe; Ben-Neriah, Yinon.

Nature ; 586(7827): 133-138, 2020 10.

Article in English | MEDLINE | ID: mdl-32728212

5.

Immunity in acute myeloid leukemia: Where the immune response and targeted therapy meet.

Fink, Avner; Hung, Eric; Singh, Indranil; Ben-Neriah, Yinon.

Eur J Immunol ; 52(1): 34-43, 2022 01.

Article in English | MEDLINE | ID: mdl-34648664

6.

Inflammation meets cancer, with NF-κB as the matchmaker.

Ben-Neriah, Yinon; Karin, Michael.

Nat Immunol ; 12(8): 715-23, 2011 Jul 19.

Article in English | MEDLINE | ID: mdl-21772280

7.

Epithelial microRNAs regulate gut mucosal immunity via epithelium-T cell crosstalk.

Biton, Moshe; Levin, Avi; Slyper, Michal; Alkalay, Irit; Horwitz, Elad; Mor, Hagar; Kredo-Russo, Sharon; Avnit-Sagi, Tali; Cojocaru, Gady; Zreik, Farid; Bentwich, Zvi; Poy, Matthew N; Artis, David; Walker, Michael D; Hornstein, Eran; Pikarsky, Eli; Ben-Neriah, Yinon.

Nat Immunol ; 12(3): 239-46, 2011 Mar.

Article in English | MEDLINE | ID: mdl-21278735

8.

Casein kinase 1-epsilon or 1-delta required for Wnt-mediated intestinal stem cell maintenance.

Morgenstern, Yael; Das Adhikari, Upasana; Ayyash, Muneef; Elyada, Ela; Tóth, Beáta; Moor, Andreas; Itzkovitz, Shalev; Ben-Neriah, Yinon.

EMBO J ; 36(20): 3046-3061, 2017 10 16.

Article in English | MEDLINE | ID: mdl-28963394

9.

CK1α ablation in keratinocytes induces p53-dependent, sunburn-protective skin hyperpigmentation.

Chang, Chung-Hsing; Kuo, Che-Jung; Ito, Takamichi; Su, Yu-Ya; Jiang, Si-Tse; Chiu, Min-Hsi; Lin, Yi-Hsiung; Nist, Andrea; Mernberger, Marco; Stiewe, Thorsten; Ito, Shosuke; Wakamatsu, Kazumasa; Hsueh, Yi-An; Shieh, Sheau-Yann; Snir-Alkalay, Irit; Ben-Neriah, Yinon.

Proc Natl Acad Sci U S A ; 114(38): E8035-E8044, 2017 09 19.

Article in English | MEDLINE | ID: mdl-28878021

10.

ß-TrCP upregulates HIF-1 in prostate cancer cells.

Cohen, Maya; Amir, Sharon; Golan, Maya; Ben-Neriah, Yinon; Mabjeesh, Nicola J.

Prostate ; 79(4): 403-413, 2019 03.

Article in English | MEDLINE | ID: mdl-30488478

11.

mTOR generates an auto-amplification loop by triggering the ßTrCP- and CK1α-dependent degradation of DEPTOR.

Duan, Shanshan; Skaar, Jeffrey R; Kuchay, Shafi; Toschi, Alfredo; Kanarek, Naama; Ben-Neriah, Yinon; Pagano, Michele.

Mol Cell ; 44(2): 317-24, 2011 Oct 21.

Article in English | MEDLINE | ID: mdl-22017877

12.

Senescence-associated inflammatory responses: aging and cancer perspectives.

Lasry, Audrey; Ben-Neriah, Yinon.

Trends Immunol ; 36(4): 217-28, 2015 Apr.

Article in English | MEDLINE | ID: mdl-25801910

13.

Spermatogenesis rescue in a mouse deficient for the ubiquitin ligase SCF{beta}-TrCP by single substrate depletion.

Kanarek, Naama; Horwitz, Elad; Mayan, Inbal; Leshets, Michael; Cojocaru, Gady; Davis, Matti; Tsuberi, Ben-Zion; Pikarsky, Eli; Pagano, Michele; Ben-Neriah, Yinon.

Genes Dev ; 24(5): 470-7, 2010 Mar 01.

Article in English | MEDLINE | ID: mdl-20194439

14.

CKIα ablation highlights a critical role for p53 in invasiveness control.

Elyada, Ela; Pribluda, Ariel; Goldstein, Robert E; Morgenstern, Yael; Brachya, Guy; Cojocaru, Gady; Snir-Alkalay, Irit; Burstain, Ido; Haffner-Krausz, Rebecca; Jung, Steffen; Wiener, Zoltan; Alitalo, Kari; Oren, Moshe; Pikarsky, Eli; Ben-Neriah, Yinon.

Nature ; 470(7334): 409-13, 2011 Feb 17.

Article in English | MEDLINE | ID: mdl-21331045

15.

Oncogenic mutations in intestinal adenomas regulate Bim-mediated apoptosis induced by TGF-ß.

Wiener, Zoltán; Band, Arja M; Kallio, Pauliina; Högström, Jenny; Hyvönen, Ville; Kaijalainen, Seppo; Ritvos, Olli; Haglund, Caj; Kruuna, Olli; Robine, Sylvie; Louvard, Daniel; Ben-Neriah, Yinon; Alitalo, Kari.

Proc Natl Acad Sci U S A ; 111(21): E2229-36, 2014 May 27.

Article in English | MEDLINE | ID: mdl-24825889

16.

Acquisition of an immunosuppressive protumorigenic macrophage phenotype depending on c-Jun phosphorylation.

Hefetz-Sela, Simona; Stein, Ilan; Klieger, Yair; Porat, Rinnat; Sade-Feldman, Moshe; Zreik, Farid; Nagler, Arnon; Pappo, Orit; Quagliata, Luca; Dazert, Eva; Eferl, Robert; Terracciano, Luigi; Wagner, Erwin F; Ben-Neriah, Yinon; Baniyash, Michal; Pikarsky, Eli.

Proc Natl Acad Sci U S A ; 111(49): 17582-7, 2014 Dec 09.

Article in English | MEDLINE | ID: mdl-25422452

17.

Critical role for IL-1ß in DNA damage-induced mucositis.

Kanarek, Naama; Grivennikov, Sergei I; Leshets, Michael; Lasry, Audrey; Alkalay, Irit; Horwitz, Elad; Shaul, Yoav D; Stachler, Matthew; Voronov, Elena; Apte, Ron N; Pagano, Michele; Pikarsky, Eli; Karin, Michael; Ghosh, Sankar; Ben-Neriah, Yinon.

Proc Natl Acad Sci U S A ; 111(6): E702-11, 2014 Feb 11.

Article in English | MEDLINE | ID: mdl-24469832

18.

Regulation of NF-κB by ubiquitination and degradation of the IκBs.

Kanarek, Naama; Ben-Neriah, Yinon.

Immunol Rev ; 246(1): 77-94, 2012 Mar.

Article in English | MEDLINE | ID: mdl-22435548

19.

Metalloprotease type III effectors that specifically cleave JNK and NF-κB.

Baruch, Kobi; Gur-Arie, Lihi; Nadler, Chen; Koby, Simi; Yerushalmi, Gal; Ben-Neriah, Yinon; Yogev, Orli; Shaulian, Eitan; Guttman, Chen; Zarivach, Raz; Rosenshine, Ilan.

EMBO J ; 30(1): 221-31, 2011 Jan 05.

Article in English | MEDLINE | ID: mdl-21113130

20.

Tissue-Predisposition to Cancer Driver Mutations.

Peters, Luriano; Venkatachalam, Avanthika; Ben-Neriah, Yinon.

Cells ; 13(2)2024 01 05.

Article in English | MEDLINE | ID: mdl-38247798

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